Book Abstract

Cytotoxicity Mechanisms of Cellular Injury and Defense offers a comprehensive exploration into how cells are damaged by internal and external threats?and how they defend and recover. Tailored for cell biologists, toxicologists, pathologists, and translational scientists, Cytotoxicity Mechanisms of Cellular Injury and Defense synthesizes detailed mechanisms with clinical relevance. It illuminates how cells sustain themselves against damage and how this knowledge can lead to innovative strategies to treat injury-related diseases. This book lays a foundation by defining cytotoxicity and the factors that lead to cell damage: oxidative stress, mitochondrial dysfunction, DNA damage, membrane disruption, and protein misfolding. It explores how these events are triggered by environmental toxins (e.g., chemicals, radiation), pathogens (viruses, bacteria), and mechanical stresses.

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