Book Abstract
Congenital Heart Defects: Breakthroughs and Progress chronicles the rapid evolution in understanding, diagnosing, and treating congenital cardiac anomalies. Drawing on groundbreaking research and clinical case studies, this volume bridges basic science with transformative therapeutic advances.
Designed for pediatric cardiologists, cardiac surgeons, geneticists, interventionalists, and researchers, Congenital Heart Defects: Breakthroughs and Progress synthesizes decades of achievement into a roadmap for future innovation. It underscores how a deep molecular understanding, coupled with cutting-edge imaging and interventional technologies, is reshaping care and improving lifespan and quality of life for patients with congenital heart anomalies.
The book delves into developmental cardiology, highlighting key genetic pathways?such as NOTCH, NKX2-5, GATA4, and TBX5?that govern cardiac morphogenesis. It explores how genetic variants and epigenetic factors contribute to the spectrum of defects, from septal abnormalities to complex conotruncal malformations.
